Ontology highlight
ABSTRACT:
SUBMITTER: Cheng H
PROVIDER: S-EPMC3684396 | biostudies-literature | 2010 Aug
REPOSITORIES: biostudies-literature
Cheng Hongqiang H Kimura Kensuke K Peter Angela K AK Cui Li L Ouyang Kunfu K Shen Tao T Liu Yujie Y Gu Yusu Y Dalton Nancy D ND Evans Sylvia M SM Knowlton Kirk U KU Peterson Kirk L KL Chen Ju J
Circulation research 20100610 3
<h4>Rationale</h4>The Z-line, alternatively termed the Z-band or Z-disc, is a highly ordered structure at the border between 2 sarcomeres. Enigma subfamily proteins (Enigma, Enigma homolog protein, and Cypher) of the PDZ-LIM domain protein family are Z-line proteins. Among the Enigma subfamily, Cypher has been demonstrated to play a pivotal role in the structure and function of striated muscle, whereas the role of Enigma homolog protein (ENH) in muscle remains largely unknown.<h4>Objective</h4>W ...[more]