Ontology highlight
ABSTRACT:
SUBMITTER: Ontawong A
PROVIDER: S-EPMC3686068 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Ontawong Atcharaporn A Saowakon Naruwan N Vivithanaporn Pornpun P Pongchaidecha Anchalee A Lailerd Narissara N Amornlerdpison Doungporn D Lungkaphin Anusorn A Srimaroeng Chutima C
BioMed research international 20130603
Spirogyra neglecta extract (SNE) has shown antihyperglycemia and antihyperlipidemia in type 2 diabetic mellitus (T2DM) rats. This study investigated the antioxidant and renoprotective effects of SNE in T2DM rats induced by high-fat diet with low-single dose streptozotocin. T2DM rats were fed daily with SNE (0.25, 0.5, and 1 g/kg BW) for 12 weeks. Renal morphology, malondialdehyde levels, qPCR, and western blotting were analyzed. Renal cortical slices were used to determine renal transport of org ...[more]