Ontology highlight
ABSTRACT:
SUBMITTER: Garcia-Closas M
PROVIDER: S-EPMC3688270 | biostudies-literature | 2013 Apr
REPOSITORIES: biostudies-literature
Garcia-Closas Montserrat M Rothman Nathaniel N Figueroa Jonine D JD Prokunina-Olsson Ludmila L Han Summer S SS Baris Dalsu D Jacobs Eric J EJ Malats Nuria N De Vivo Immaculata I Albanes Demetrius D Purdue Mark P MP Sharma Sapna S Fu Yi-Ping YP Kogevinas Manolis M Wang Zhaoming Z Tang Wei W Tardón Adonina A Serra Consol C Carrato Alfredo A García-Closas Reina R Lloreta Josep J Johnson Alison A Schwenn Molly M Karagas Margaret R MR Schned Alan A Andriole Gerald G Grubb Robert R Black Amanda A Gapstur Susan M SM Thun Michael M Diver William Ryan WR Weinstein Stephanie J SJ Virtamo Jarmo J Hunter David J DJ Caporaso Neil N Landi Maria Teresa MT Hutchinson Amy A Burdett Laurie L Jacobs Kevin B KB Yeager Meredith M Fraumeni Joseph F JF Chanock Stephen J SJ Silverman Debra T DT Chatterjee Nilanjan N
Cancer research 20130327 7
Bladder cancer results from the combined effects of environmental and genetic factors, smoking being the strongest risk factor. Evaluating absolute risks resulting from the joint effects of smoking and genetic factors is critical to assess the public health relevance of genetic information. Analyses included up to 3,942 cases and 5,680 controls of European background in seven studies. We tested for multiplicative and additive interactions between smoking and 12 susceptibility loci, individually ...[more]