Ontology highlight
ABSTRACT:
SUBMITTER: Keliher EJ
PROVIDER: S-EPMC3689232 | biostudies-literature | 2013 Jul
REPOSITORIES: biostudies-literature
Neoplasia (New York, N.Y.) 20130701 7
When resectable, invasive pancreatic ductal adenocarcinoma (PDAC) is most commonly treated with surgery and radiochemotherapy. Given the intricate local anatomy and locoregional mode of dissemination, achieving clean surgical margins can be a significant challenge. On the basis of observations that cathepsin E (CTSE) is overexpressed in PDAC and that an United States Food and Drug Administration (FDA)-approved protease inhibitor has high affinity for CTSE, we have developed a CTSE optical imagin ...[more]