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Long noncoding RNAs-related diseases, cancers, and drugs.


ABSTRACT: Long noncoding RNA (lncRNA) function is described in terms of related gene expressions, diseases, and cancers as well as their polymorphisms. Potential modulators of lncRNA function, including clinical drugs, natural products, and derivatives, are discussed, and bioinformatic resources are summarized. The improving knowledge of the lncRNA regulatory network has implications not only in gene expression, diseases, and cancers, but also in the development of lncRNA-based pharmacology.

SUBMITTER: Tang JY 

PROVIDER: S-EPMC3690748 | biostudies-literature | 2013

REPOSITORIES: biostudies-literature

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Long noncoding RNAs-related diseases, cancers, and drugs.

Tang Jen-Yang JY   Lee Jin-Ching JC   Chang Yung-Ting YT   Hou Ming-Feng MF   Huang Hurng-Wern HW   Liaw Chih-Chuang CC   Chang Hsueh-Wei HW  

TheScientificWorldJournal 20130606


Long noncoding RNA (lncRNA) function is described in terms of related gene expressions, diseases, and cancers as well as their polymorphisms. Potential modulators of lncRNA function, including clinical drugs, natural products, and derivatives, are discussed, and bioinformatic resources are summarized. The improving knowledge of the lncRNA regulatory network has implications not only in gene expression, diseases, and cancers, but also in the development of lncRNA-based pharmacology. ...[more]

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