Effects of aging and smoking on carotid intima-media thickness in HIV-infection.

ABSTRACT:

Objectives

To investigate the effects of aging and smoking on carotid intima-media thickness (cIMT) among patients with and without HIV.

Methods

Data from a community sample of HIV-infected and HIV-uninfected participants were analyzed. Carotid intima-media thickness was measured via carotid ultrasound and smoking history was obtained via patient interview.

Results

Data on 166 male and female participants with stable HIV-infection and 152 healthy HIV-uninfected participants were analyzed. Among the HIV-infected and HIV-uninfected participants, a significant association was observed between age and cIMT [r = 0.51, P < 0.0001 (HIV), r = 0.39, P < 0.0001, (non-HIV)], and between smoking burden and cIMT [r = 0.42, P < 0.0001 (HIV), r = 0.24, P = 0.003 (non-HIV)]. In multi

SUBMITTER: Fitch KV 

PROVIDER: S-EPMC3690796 | biostudies-literature | 2013 Jan

REPOSITORIES: biostudies-literature