Baseline cognitive function, recurrent stroke, and risk of dementia in patients with stroke.

ABSTRACT:

Background and purpose

To determine the interrelationships between baseline Mini-Mental State Examination (MMSE) score and risk of overall dementia, post-recurrent stroke dementia, and dementia without recurrent stroke among patients with a history of stroke.

Methods

Prospective cohort study among participants enrolled in the Perindopril Protection Against Recurrent Stroke Study (PROGRESS) for whom baseline MMSE score was available. Baseline MMSE score was divided into 4 categories: 30, 29-27, 26-24, and <24. Participants were followed for incident dementia and recurrent stroke. Logistic regression models were used to examine the association between MMSE score and dementia.

Results

Of the 6080 participants included in this analysis, 2493 had an MMSE score of 30, 1768

SUBMITTER: Rist PM 

PROVIDER: S-EPMC3695012 | biostudies-literature | 2013 Jul

REPOSITORIES: biostudies-literature