Ontology highlight
ABSTRACT:
SUBMITTER: Tang Q
PROVIDER: S-EPMC3695644 | biostudies-literature | 2012 Feb
REPOSITORIES: biostudies-literature
Journal of molecular cell biology 20111214 1
Regulatory T cells (Tregs) are long-lived cells that suppress immune responses in vivo in a dominant and antigen-specific manner. Therefore, therapeutic application of Tregs to control unwanted immune responses is an active area of investigation. Tregs can confer long-term protection against auto-inflammatory diseases in mouse models. They have also been shown to be effective in suppressing alloimmunity in models of graft-versus-host disease and organ transplantation. Building on extensive resea ...[more]