Ontology highlight
ABSTRACT:
SUBMITTER: Braskie MN
PROVIDER: S-EPMC3696063 | biostudies-literature | 2012 Sep-Oct
REPOSITORIES: biostudies-literature
Braskie Meredith N MN Jahanshad Neda N Toga Arthur W AW McMahon Katie L KL de Zubicaray Greig I GI Martin Nicholas G NG Wright Margaret J MJ Thompson Paul M PM
Bioarchitecture 20120901 5
Growth factors and their receptors are important for cellular migration as well as axonal guidance and myelination in the brain. They also play a key role in programmed cell death, and are implicated in a number of mental illnesses. Recently, we reported that healthy young adults who carry the T allele variant in the growth factor gene, NTRK1 (at location rs6336), had lower white matter integrity than non-carriers on diffusion images of the brain. Diffusion tensor imaging (DTI) revealed how this ...[more]