Mapping the telomere integrated genome of human herpesvirus 6A and 6B.
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ABSTRACT:
SUBMITTER: Arbuckle JH
PROVIDER: S-EPMC3696530 | biostudies-literature | 2013 Jul
REPOSITORIES: biostudies-literature
Publications
Mapping the telomere integrated genome of human herpesvirus 6A and 6B.
Arbuckle Jesse H JH Pantry Shara N SN Medveczky Maria M MM Prichett Joshua J Loomis Kristin S KS Ablashi Dharam D Medveczky Peter G PG
Virology 20130504 1
Human herpesvirus 6B (HHV-6B) is the causative agent of roseola infantum. HHV-6A and 6B can reactivate in immunosuppressed individuals and are linked with severe inflammatory response, organ rejection and central nervous system diseases. About 0.85% of the US and UK population carries an integrated HHV-6 genome in all nucleated cells through germline transmission. We have previously reported that the HHV-6A genome integrated in telomeres of patients suffering from neurological dysfunction and al ...[more]
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