Ontology highlight
ABSTRACT:
SUBMITTER: Zheng Y
PROVIDER: S-EPMC3697898 | biostudies-literature | 2013 Jul
REPOSITORIES: biostudies-literature
Zheng Yonglan Y Ogundiran Temidayo O TO Falusi Adeyinka G AG Nathanson Katherine L KL John Esther M EM Hennis Anselm J M AJ Ambs Stefan S Domchek Susan M SM Rebbeck Timothy R TR Simon Michael S MS Nemesure Barbara B Wu Suh-Yuh SY Leske Maria Cristina MC Odetunde Abayomi A Niu Qun Q Zhang Jing J Afolabi Chibuzor C Gamazon Eric R ER Cox Nancy J NJ Olopade Christopher O CO Olopade Olufunmilayo I OI Huo Dezheng D
Carcinogenesis 20130308 7
Numerous single nucleotide polymorphisms (SNPs) associated with breast cancer susceptibility have been identified by genome-wide association studies (GWAS). However, these SNPs were primarily discovered and validated in women of European and Asian ancestry. Because linkage disequilibrium is ancestry-dependent and heterogeneous among racial/ethnic populations, we evaluated common genetic variants at 22 GWAS-identified breast cancer susceptibility loci in a pooled sample of 1502 breast cancer case ...[more]