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The aurora B kinase promotes inner and outer kinetochore interactions in budding yeast.

ABSTRACT: The kinetochore is the macromolecular protein complex that mediates chromosome segregation. The Dsn1 component is crucial for kinetochore assembly and is phosphorylated by the Aurora B kinase. We found that Aurora B phosphorylation of Dsn1 promotes the interaction between outer and inner kinetochore proteins in budding yeast.

SUBMITTER: Akiyoshi B 

PROVIDER: S-EPMC3697981 | biostudies-literature |

REPOSITORIES: biostudies-literature

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