Unknown

Dataset Information

0

The aurora B kinase promotes inner and outer kinetochore interactions in budding yeast.


ABSTRACT: The kinetochore is the macromolecular protein complex that mediates chromosome segregation. The Dsn1 component is crucial for kinetochore assembly and is phosphorylated by the Aurora B kinase. We found that Aurora B phosphorylation of Dsn1 promotes the interaction between outer and inner kinetochore proteins in budding yeast.

SUBMITTER: Akiyoshi B 

PROVIDER: S-EPMC3697981 | biostudies-literature | 2013 Jul

REPOSITORIES: biostudies-literature

altmetric image

Publications

The aurora B kinase promotes inner and outer kinetochore interactions in budding yeast.

Akiyoshi Bungo B   Nelson Christian R CR   Biggins Sue S  

Genetics 20130501 3


The kinetochore is the macromolecular protein complex that mediates chromosome segregation. The Dsn1 component is crucial for kinetochore assembly and is phosphorylated by the Aurora B kinase. We found that Aurora B phosphorylation of Dsn1 promotes the interaction between outer and inner kinetochore proteins in budding yeast. ...[more]

Similar Datasets

| S-EPMC6781445 | biostudies-literature
| S-EPMC8441410 | biostudies-literature
| S-EPMC3252399 | biostudies-literature
| S-EPMC8082439 | biostudies-literature
| S-EPMC149985 | biostudies-literature
| S-EPMC155308 | biostudies-literature
| S-EPMC4596668 | biostudies-literature
| S-EPMC10381965 | biostudies-literature
| S-EPMC3871439 | biostudies-literature
| S-EPMC2172676 | biostudies-literature