Ontology highlight
ABSTRACT:
SUBMITTER: Turel I
PROVIDER: S-EPMC3698415 | biostudies-literature | 2010 Dec
REPOSITORIES: biostudies-literature
Turel Iztok I Kljun Jakob J Perdih Franc F Morozova Elena E Bakulev Vladimir V Kasyanenko Nina N Byl Jo Ann W JA Osheroff Neil N
Inorganic chemistry 20101026 23
An organometallic ruthenium complex of quinolone antibacterial agent ofloxacin, [(η(6)-p-cymene)RuCl(O,O-oflo)]·2.8H(2)O (1·2.8H(2)O), was isolated, and its crystal structure was determined. In this "piano-stool" complex, quinolone is bidentately coordinated to the metal through the ring carbonyl and one of the carboxylic oxygen atoms. Interactions of the title complex with DNA were studied by spectroscopic methods [electronic, fluorescence, and circular dichroism (CD)] and atomic force microsco ...[more]