Factors associated with mortality of HIV-positive clients receiving methadone maintenance treatment in China.

ABSTRACT:

Background

Little is known about mortality of opiate users attending methadone maintenance treatment (MMT) clinics. We sought to investigate mortality and its predictors among human immunodeficiency virus (HIV)-positive MMT clients.

Methods

Records of 306 786 clients enrolled in China's MMT program from 24 March 2004 to 30 April 2011 were abstracted. Mortality rates were calculated for all HIV-positive antiretroviral treatment (ART)-naive and ART-experienced clients. Risk factors were examined using stratified proportional hazard ratios (HRs).

Results

The observed mortality rate for all clients was 11.8/1000 person-years (PY, 95% confidence interval [CI], 11.5-12.1) and 57.2/1000 PY (CI, 54.9-59.4) for HIV-positive clients (n = 18 193). An increase in average methadon

SUBMITTER: Liu E 

PROVIDER: S-EPMC3698997 | biostudies-literature | 2013 Aug

REPOSITORIES: biostudies-literature