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Pathway Processor 2.0: a web resource for pathway-based analysis of high-throughput data.


ABSTRACT:

Summary

Pathway Processor 2.0 is a web application designed to analyze high-throughput datasets, including but not limited to microarray and next-generation sequencing, using a pathway centric logic. In addition to well-established methods such as the Fisher's test and impact analysis, Pathway Processor 2.0 offers innovative methods that convert gene expression into pathway expression, leading to the identification of differentially regulated pathways in a dataset of choice.

Availability and implementation

Pathway Processor 2.0 is available as a web service at http://compbiotoolbox.fmach.it/pathwayProcessor/. Sample datasets to test the functionality can be used directly from the application.

Contact

duccio.cavalieri@fmach.it

Supplementary information

Supplementary data are available at Bioinformatics online.

SUBMITTER: Beltrame L 

PROVIDER: S-EPMC3702260 | biostudies-literature | 2013 Jul

REPOSITORIES: biostudies-literature

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Publications

Pathway Processor 2.0: a web resource for pathway-based analysis of high-throughput data.

Beltrame Luca L   Bianco Luca L   Fontana Paolo P   Cavalieri Duccio D  

Bioinformatics (Oxford, England) 20130605 14


<h4>Summary</h4>Pathway Processor 2.0 is a web application designed to analyze high-throughput datasets, including but not limited to microarray and next-generation sequencing, using a pathway centric logic. In addition to well-established methods such as the Fisher's test and impact analysis, Pathway Processor 2.0 offers innovative methods that convert gene expression into pathway expression, leading to the identification of differentially regulated pathways in a dataset of choice.<h4>Availabil  ...[more]

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