Metabolic engineering of Escherichia coli for the production of xylonate.
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ABSTRACT:
SUBMITTER: Cao Y
PROVIDER: S-EPMC3702539 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Publications
Metabolic engineering of Escherichia coli for the production of xylonate.
Cao Yujin Y Xian Mo M Zou Huibin H Zhang Haibo H
PloS one 20130705 7
Xylonate is a valuable chemical for versatile applications. Although the chemical synthesis route and microbial conversion pathway were established decades ago, no commercial production of xylonate has been obtained so far. In this study, the industrially important microorganism Escherichia coli was engineered to produce xylonate from xylose. Through the coexpression of a xylose dehydrogenase (xdh) and a xylonolactonase (xylC) from Caulobacter crescentus, the recombinant strain could convert 1 g ...[more]
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