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ABSTRACT:
SUBMITTER: Menon V
PROVIDER: S-EPMC3703203 | biostudies-literature | 2013 Jun
REPOSITORIES: biostudies-literature
Menon Vilas V Vallat Brinda K BK Dybas Joseph M JM Fiser Andras A
Structure (London, England : 1993) 20130516 6
A remaining challenge in protein modeling is to predict structures for sequences with no sequence similarity to any experimentally solved structure. Based on earlier observations, the library of protein backbone supersecondary structure motifs (Smotifs) saturated about a decade ago. Therefore, it should be possible to build any structure from a combination of existing Smotifs with the help of limited experimental data that are sufficient to relate the backbone conformations of Smotifs between ta ...[more]