Plasma adiponectin and mortality in critically ill subjects with acute respiratory failure.

ABSTRACT:

Objective

: Adiponectin, an anti-inflammatory cytokine produced by adipose tissue, has been shown to modulate survival in animal models of critical illness. We examined the association between plasma adiponectin and clinical outcomes in critically ill patients with acute respiratory failure.

Design

: Secondary analysis of a single-center, randomized controlled trial.

Setting

: Medical intensive care unit of a university-based, tertiary medical center.

Patients

: One hundred seventy-five subjects with acute respiratory failure enrolled in randomized, controlled pilot trial of Early versus Delayed Enternal Nutrition (EDEN pilot study).

Interventions

: None.

Measurements and main results

: Adiponectin measured within 48 hrs of respiratory failure (Ap

SUBMITTER: Walkey AJ 

PROVIDER: S-EPMC3703623 | biostudies-literature | 2010 Dec

REPOSITORIES: biostudies-literature