Ontology highlight
ABSTRACT:
SUBMITTER: Sosinsky GE
PROVIDER: S-EPMC3704572 | biostudies-literature | 2011 May-Jun
REPOSITORIES: biostudies-literature
Sosinsky Gina E GE Boassa Daniela D Dermietzel Rolf R Duffy Heather S HS Laird Dale W DW MacVicar Brian B Naus Christian C CC Penuela Silvia S Scemes Eliana E Spray David C DC Thompson Roger J RJ Zhao Hong-Bo HB Dahl Gerhard G
Channels (Austin, Tex.) 20110501 3
Pannexins, a class of membrane channels, bear significant sequence homology with the invertebrate gap junction proteins, innexins and more distant similarities in their membrane topologies and pharmacological sensitivities with the gap junction proteins, connexins. However, the functional role for the pannexin oligomers, or pannexons, is different from connexin oligomers, the connexons. Many pannexin publications have used the term "hemichannels" to describe pannexin oligomers while others use t ...[more]