Ontology highlight
ABSTRACT:
SUBMITTER: Korotkov KV
PROVIDER: S-EPMC3705712 | biostudies-literature | 2012 Apr
REPOSITORIES: biostudies-literature
Nature reviews. Microbiology 20120402 5
Many gram-negative bacteria use the sophisticated type II secretion system (T2SS) to translocate a wide range of proteins from the periplasm across the outer membrane. The inner-membrane platform of the T2SS is the nexus of the system and orchestrates the secretion process through its interactions with the periplasmic filamentous pseudopilus, the dodecameric outer-membrane complex and a cytoplasmic secretion ATPase. Here, recent structural and biochemical information is reviewed to describe our ...[more]