Ontology highlight
ABSTRACT:
SUBMITTER: Kreitzer FR
PROVIDER: S-EPMC3708511 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Kreitzer Faith R FR Salomonis Nathan N Sheehan Alice A Huang Miller M Park Jason S JS Spindler Matthew J MJ Lizarraga Paweena P Weiss William A WA So Po-Lin PL Conklin Bruce R BR
American journal of stem cells 20130630 2
Neural crest (NC) cells contribute to the development of many complex tissues of all three germ layers during embryogenesis, and its abnormal development accounts for several congenital birth defects. Generating NC cells-including specific subpopulations such as cranial, cardiac, and trunk NC cells-from human pluripotent stem cells will provide a valuable model system to study human development and disease. Here, we describe a rapid and robust NC differentiation method called "LSB-short" that is ...[more]