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The global epidemiology of clonorchiasis and its relation with cholangiocarcinoma.

ABSTRACT: This paper reviews the epidemiological status and characteristics of clonorchiasis at global level and the etiological relationship between Clonorchis sinensis infection and cholangiocarcinoma (CCA). A conservative estimation was made that 15 million people were infected in the world in 2004, of which over 85% distributed in China. The epidemiology of clonorchiasis is characterized by rising trend in its prevalence, variability among sexes and age, as well as endemicity in different regions. More data indicate that C. sinensis infection is carcinogenic to human, and it is predicted that nearly 5 000 CCA cases attributed to C. sinensis infection may occur annually in the world decades later, with its overall odds ratio of 4.47. Clonorchiasis is becoming one major public health problem in east Asia, and it is worthwhile to carry out further epidemiological studies.

SUBMITTER: Qian MB

PROVIDER: S-EPMC3710150 | biostudies-literature | 2012 Oct

REPOSITORIES: biostudies-literature

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The global epidemiology of clonorchiasis and its relation with cholangiocarcinoma.

Qian Men-Bao MB Chen Ying-Dan YD Liang Song S Yang Guo-Jing GJ Zhou Xiao-Nong XN

Infectious diseases of poverty 20121025 1

This paper reviews the epidemiological status and characteristics of clonorchiasis at global level and the etiological relationship between Clonorchis sinensis infection and cholangiocarcinoma (CCA). A conservative estimation was made that 15 million people were infected in the world in 2004, of which over 85% distributed in China. The epidemiology of clonorchiasis is characterized by rising trend in its prevalence, variability among sexes and age, as well as endemicity in different regions. Mor ...[more]

PMID: 23849183

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