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Phosphate binding with a thiophene-based azamacrocycle in water.

ABSTRACT: Structural characterization of the phosphate complex with a thiophene-based macrocycle suggests that two dihydrogen phosphates in a dimeric form are encapsulated in the cavity via several hydrogen bonds from NH···O and CH···O interactions. In the lattice framework, the two dimers are linearly hydrogen-bonded to form a tetramer. 1H NMR titrations suggest that the host forms a 1:1 complex with phosphate, showing an association constant of 120 M-1 in D2O at pH = 5.5. The host guest complexation was further confirmed by ESI-MS in a gas phase.

SUBMITTER: Saeed MA

PROVIDER: S-EPMC3714117 | biostudies-literature | 2012 Jul

REPOSITORIES: biostudies-literature

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Phosphate binding with a thiophene-based azamacrocycle in water.

Saeed Musabbir A MA Pramanik Avijit A Hossain Md Alamgir MA

Inorganic chemistry communications 20120701

Structural characterization of the phosphate complex with a thiophene-based macrocycle suggests that two dihydrogen phosphates in a dimeric form are encapsulated in the cavity via several hydrogen bonds from NH···O and CH···O interactions. In the lattice framework, the two dimers are linearly hydrogen-bonded to form a tetramer. 1H NMR titrations suggest that the host forms a 1:1 complex with phosphate, showing an association constant of 120 M-1 in D2O at pH = 5.5 ...[more]

PMID: 23874145

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