Ontology highlight
ABSTRACT:
SUBMITTER: Markovic A
PROVIDER: S-EPMC3715045 | biostudies-literature | 2012 Sep
REPOSITORIES: biostudies-literature
Markovic Ana A Chung Christine H CH
Expert review of anticancer therapy 20120901 9
New agents and treatment strategies that can be safely and effectively integrated into current treatment paradigms for head and neck squamous cell carcinoma (HNSCC) are urgently needed. To date, the anti-EGF receptor (EGFR) monoclonal antibody, cetuximab, is the first and only molecularly targeted therapy to demonstrate a survival benefit for patients with recurrent or metastatic disease. Other anti-EGFR-targeted therapies, including monoclonal antibodies (e.g., panitumumab and zalutumumab) and ...[more]