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Detection of New Delhi metallo-?-lactamase (encoded by blaNDM-1) in Acinetobacter schindleri during routine surveillance.

ABSTRACT: A carbapenem-resistant Alcaligenes faecalis strain was isolated from a surveillance swab of a service member injured in Afghanistan. The isolate was positive for bla(NDM) by real-time PCR. Species identification was reevaluated on three identification systems but was inconclusive. Genome sequencing indicated that the closest relative was Acinetobacter schindleri and that bla(NDM-1) was carried on a plasmid that shared >99% identity with one identified in an Acinetobacter lwoffii isolate. The isolate also carried a novel chromosomally encoded class D oxacillinase.

SUBMITTER: McGann P 

PROVIDER: S-EPMC3716100 | biostudies-literature | 2013 Jun

REPOSITORIES: biostudies-literature

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Detection of New Delhi metallo-β-lactamase (encoded by blaNDM-1) in Acinetobacter schindleri during routine surveillance.

McGann Patrick P   Milillo Michael M   Clifford Robert J RJ   Snesrud Erik E   Stevenson Lindsay L   Backlund Michael G MG   Viscount Helen B HB   Quintero Reyes R   Kwak Yoon I YI   Zapor Michael J MJ   Waterman Paige E PE   Lesho Emil P EP  

Journal of clinical microbiology 20130403 6

A carbapenem-resistant Alcaligenes faecalis strain was isolated from a surveillance swab of a service member injured in Afghanistan. The isolate was positive for bla(NDM) by real-time PCR. Species identification was reevaluated on three identification systems but was inconclusive. Genome sequencing indicated that the closest relative was Acinetobacter schindleri and that bla(NDM-1) was carried on a plasmid that shared >99% identity with one identified in an Acinetobacter lwoffii isolate. The iso  ...[more]

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