Ontology highlight
ABSTRACT:
SUBMITTER: Pace HP
PROVIDER: S-EPMC3717335 | biostudies-literature | 2013 Jun
REPOSITORIES: biostudies-literature
Pace Hudson P HP Sherrod Stacy D SD Monson Christopher F CF Russell David H DH Cremer Paul S PS
Analytical chemistry 20130603 12
Herein, we describe a new analytical platform utilizing advances in heterogeneous supported lipid bilayer (SLB) electrophoresis and matrix-assisted laser desorption/ionization-mass spectrometry (MALDI-MS) imaging. This platform allowed for the separation and visualization of both charged and neutral lipid membrane components without the need for extrinsic labels. A heterogeneous SLB was created using vesicles containing monosialoganglioside GM1, disialoganglioside GD1b, POPC, as well as the orth ...[more]