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Abnormal fusiform activation during emotional-face encoding assessed with functional magnetic resonance imaging.

ABSTRACT: This functional magnetic resonance imaging study shows that children and adults with bipolar disorder (BD), compared with healthy subjects, exhibit impaired memory for emotional faces and abnormal fusiform activation during encoding. Fusiform activation abnormalities in BD were correlated with mania severity and may therefore represent a trait and state BD biomarker.

SUBMITTER: Adleman NE 

PROVIDER: S-EPMC3717571 | biostudies-literature | 2013 May

REPOSITORIES: biostudies-literature

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Abnormal fusiform activation during emotional-face encoding assessed with functional magnetic resonance imaging.

Adleman Nancy E NE   Kayser Reilly R RR   Olsavsky Aviva K AK   Bones Brian L BL   Muhrer Eli J EJ   Fromm Stephen J SJ   Pine Daniel S DS   Zarate Carlos C   Leibenluft Ellen E   Brotman Melissa A MA  

Psychiatry research 20130329 2

This functional magnetic resonance imaging study shows that children and adults with bipolar disorder (BD), compared with healthy subjects, exhibit impaired memory for emotional faces and abnormal fusiform activation during encoding. Fusiform activation abnormalities in BD were correlated with mania severity and may therefore represent a trait and state BD biomarker. ...[more]

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