High-resolution view of bacteriophage lambda gene expression by ribosome profiling.
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ABSTRACT:
SUBMITTER: Liu X
PROVIDER: S-EPMC3718152 | biostudies-literature | 2013 Jul
REPOSITORIES: biostudies-literature
Publications
High-resolution view of bacteriophage lambda gene expression by ribosome profiling.
Liu Xiaoqiu X Jiang Huifeng H Gu Zhenglong Z Roberts Jeffrey W JW
Proceedings of the National Academy of Sciences of the United States of America 20130628 29
Bacteriophage lambda is one of the most extensively studied organisms and has been a primary model for understanding basic modes of genetic regulation. Here, we examine the progress of lambda gene expression during phage development by ribosome profiling and, thereby, provide a very-high-resolution view of lambda gene expression. The known genes are expressed in a predictable fashion, authenticating the analysis. However, many previously unappreciated potential open reading frames become apparen ...[more]
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