In vitro perfused human capillary networks.
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ABSTRACT:
SUBMITTER: Moya ML
PROVIDER: S-EPMC3719485 | biostudies-literature | 2013 Sep
REPOSITORIES: biostudies-literature
Publications
In vitro perfused human capillary networks.
Moya Monica L ML Hsu Yu-Hsiang YH Lee Abraham P AP Hughes Christopher C W CC George Steven C SC
Tissue engineering. Part C, Methods 20130221 9
Replicating in vitro the complex in vivo tissue microenvironment has the potential to transform our approach to medicine and also our understanding of biology. In order to accurately model the 3D arrangement and interaction of cells and extracellular matrix, new microphysiological systems must include a vascular supply. The vasculature not only provides the necessary convective transport of oxygen, nutrients, and waste in 3D culture, but also couples and integrates the responses of organ systems ...[more]
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