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Integrated software for analysis and synthesis of voice quality.

ABSTRACT: Voice quality is an important perceptual cue in many disciplines, but knowledge of its nature is limited by a poor understanding of the relevant psychoacoustics. This article (aimed at researchers studying voice, speech, and vocal behavior) describes the UCLA voice synthesizer, software for voice analysis and synthesis designed to test hypotheses about the relationship between acoustic parameters and voice quality perception. The synthesizer provides experimenters with a useful tool for creating and modeling voice signals. In particular, it offers an integrated approach to voice analysis and synthesis and allows easy, precise, spectral-domain manipulations of the harmonic voice source. The synthesizer operates in near real time, using a parsimonious set of acoustic parameters for the voice source and vocal tract that a user can modify to accurately copy the quality of most normal and pathological voices. The software, user's manual, and audio files may be downloaded from http://brm.psychonomic-journals.org/content/supplemental. Future updates may be downloaded from www.surgery.medsch.ucla.edu/glottalaffairs/.

SUBMITTER: Kreiman J

PROVIDER: S-EPMC3719850 | biostudies-literature | 2010 Nov

REPOSITORIES: biostudies-literature

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Integrated software for analysis and synthesis of voice quality.

Kreiman Jody J Antoñanzas-Barroso Norma N Gerratt Bruce R BR

Behavior research methods 20101101 4

Voice quality is an important perceptual cue in many disciplines, but knowledge of its nature is limited by a poor understanding of the relevant psychoacoustics. This article (aimed at researchers studying voice, speech, and vocal behavior) describes the UCLA voice synthesizer, software for voice analysis and synthesis designed to test hypotheses about the relationship between acoustic parameters and voice quality perception. The synthesizer provides experimenters with a useful tool for creating ...[more]

PMID: 21139170

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Project description:BackgroundFollowing the successful scale-up of antiretroviral therapy (ART), the focus is now on ensuring good quality of life (QoL) and sustained viral suppression in people living with HIV. The access to mobile technology in the most burdened countries is increasing rapidly, and therefore, mobile health (mHealth) technologies could be leveraged to improve QoL in people living with HIV. However, data on the impact of mHealth tools on the QoL in people living with HIV are limited to the evaluation of SMS text messaging; these are infeasible in high-illiteracy settings.ObjectiveThe primary and secondary outcomes were to determine the impact of interactive voice response (IVR) technology on Medical Outcomes Study HIV QoL scores and viral suppression at 12 months, respectively.MethodsWithin the Call for Life study, ART-experienced and ART-naïve people living with HIV commencing ART were randomized (1:1 ratio) to the control (no IVR support) or intervention arm (daily adherence and pre-appointment reminders, health information tips, and option to report symptoms). The software evaluated was Call for Life Uganda, an IVR technology that is based on the Mobile Technology for Community Health open-source software. Eligibility criteria for participation included access to a phone, fluency in local languages, and provision of consent. The differences in differences (DIDs) were computed, adjusting for baseline HIV RNA and CD4.ResultsOverall, 600 participants (413 female, 68.8%) were enrolled and followed-up for 12 months. In the intervention arm of 300 participants, 298 (99.3%) opted for IVR and 2 (0.7%) chose SMS text messaging as the mode of receiving reminders and health tips. At 12 months, there was no overall difference in the QoL between the intervention and control arms (DID=0.0; P=.99) or HIV RNA (DID=0.01; P=.94). At 12 months, 124 of the 256 (48.4%) active participants had picked up at least 50% of the calls. In the active intervention participants, high users (received >75% of reminders) had overall higher QoL compared to low users (received <25% of reminders) (92.2 versus 87.8, P=.02). Similarly, high users also had higher QoL scores in the mental health domain (93.1 versus 86.8, P=.008) and better appointment keeping. Similarly, participants with moderate use (51%-75%) had better viral suppression at 12 months (80/94, 85% versus 11/19, 58%, P=.006).ConclusionsOverall, there was high uptake and acceptability of the IVR tool. While we found no overall difference in the QoL and viral suppression between study arms, people living with HIV with higher usage of the tool showed greater improvements in QoL, viral suppression, and appointment keeping. With the declining resources available to HIV programs and the increasing number of people living with HIV accessing ART, IVR technology could be used to support patient care. The tool may be helpful in situations where physical consultations are infeasible, including the current COVID epidemic.Trial registrationClinicalTrials.gov NCT02953080; https://clinicaltrials.gov/ct2/show/NCT02953080.

Project description:PurposeThe purpose of this study is to develop a program to concatenate acoustic vowel segments that were selected with the moving window technique, a previously developed technique used to segment and select the least perturbed segment from a sustained vowel segment. The concatenated acoustic segments were compared with the nonconcatenated, short, individual acoustic segments for their ability to differentiate normal and pathological voices. The concatenation process sometimes created a clicking noise or beat, which was also analyzed to determine any confounding effects.MethodA program was developed to concatenate the moving window segments. Listeners with no previous rating experience were trained and, then, rated 20 normal and 20 pathological voice segments, both concatenated (2 s) and short (0.2 s) for a total of 80 segments. Listeners evaluated these segments on both the Grade, Roughness, Breathiness, Asthenia, and Strain scale (GRBAS; 8 listeners) and the Consensus Auditory-Perceptual Evaluation of Voice (Kempster, Gerratt, Abbott, Barkmeier-Kraemer, & Hillman, 2009) scale (7 listeners). The sensitivity and specificity of these ratings were analyzed using a receiver-operating characteristic curve. To evaluate if there were increases in particular criteria due to the beat, differences between beat and nonbeat ratings were compared using a 2-tailed analysis of variance.ResultsConcatenated segments had a higher sensitivity and specificity for distinguishing pathological and normal voices than short segments. Compared with nonbeat segments, the beat had statistically similar increases for all criteria across Consensus Auditory-Perceptual Evaluation of Voice and GRBAS scales, except pitch and loudness.ConclusionsThe concatenated moving window method showed improved sensitivity and specificity for detecting voice disorders using auditory-perceptual analysis, compared with the short moving window segment. It is a helpful tool for perceptual analytic protocols, allowing for voice evaluation using standardized and automated voice-segmenting procedures.Supplemental materialhttps://doi.org/10.23641/asha.7100951.

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Integrated software for analysis and synthesis of voice quality.

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Integrated software for analysis and synthesis of voice quality.

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