Ontology highlight
ABSTRACT:
SUBMITTER: Zhou X
PROVIDER: S-EPMC3720751 | biostudies-literature | 2013 May-Jun
REPOSITORIES: biostudies-literature
Linkers of the nucleoskeleton to the cytoskeleton (LINC) complexes formed by SUN and KASH proteins are conserved eukaryotic protein complexes that bridge the nuclear envelope (NE) via protein-protein interactions in the NE lumen. Revealed by opisthokont studies, LINC complexes are key players in multiple cellular processes, such as nuclear and chromosomal positioning and nuclear shape determination, which in turn influence the generation of gametes and several aspects of development. Although co ...[more]