S6K2: The Neglected S6 Kinase Family Member.
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ABSTRACT:
SUBMITTER: Pardo OE
PROVIDER: S-EPMC3721059 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Publications
S6K2: The Neglected S6 Kinase Family Member.
Pardo Olivier E OE Seckl Michael J MJ
Frontiers in oncology 20130724
S6 kinase 2 (S6K2) is a member of the AGC kinases super-family. Its closest homolog, S6K1, has been extensively studied along the years. However, due to the belief in the community that the high degree of identity between these two isoforms would translate in essentially identical biological functions, S6K2 has been largely neglected. Nevertheless, recent research has clearly highlighted that these two proteins significantly differ in their roles in vitro as well as in vivo. These findings are s ...[more]
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