Ontology highlight
ABSTRACT:
SUBMITTER: Woo S
PROVIDER: S-EPMC3722530 | biostudies-literature | 2013 Aug
REPOSITORIES: biostudies-literature
Woo Sangsoon S Zhang Xuekui X Sauteraud Renan R Robert François F Gottardo Raphael R
Bioinformatics (Oxford, England) 20130620 16
<h4>Summary</h4>MNase-Seq and ChIP-Seq have evolved as popular techniques to study chromatin and histone modification. Although many tools have been developed to identify enriched regions, software tools for nucleosome positioning are still limited. We introduce a flexible and powerful open-source R package, PING 2.0, for nucleosome positioning using MNase-Seq data or MNase- or sonicated- ChIP-Seq data combined with either single-end or paired-end sequencing. PING uses a model-based approach, wh ...[more]