Ontology highlight
ABSTRACT:
SUBMITTER: Bens S
PROVIDER: S-EPMC3722674 | biostudies-literature | 2013 Aug
REPOSITORIES: biostudies-literature
Bens Susanne S Haake Andrea A Richter Julia J Leohold Judith J Kolarova Julia J Vater Inga I Riepe Felix G FG Buiting Karin K Eggermann Thomas T Gillessen-Kaesbach Gabriele G Platzer Konrad K Prawitt Dirk D Caliebe Almuth A Siebert Reiner R
European journal of human genetics : EJHG 20121212 8
Various genes located at imprinted loci and regulated by epigenetic mechanisms are involved in the control of growth and differentiation. The broad phenotypic variability of imprinting disorders suggests that individuals with inborn errors of imprinting might remain undetected among patients born small for gestational age (SGA). We evaluated quantitative DNA methylation analysis at differentially methylated regions (DMRs) of 10 imprinted loci (PLAGL1, IGF2R DMR2, GRB10, H19 DMR, IGF2, MEG3, NDN, ...[more]