Ontology highlight
ABSTRACT:
SUBMITTER: Macri S
PROVIDER: S-EPMC3723657 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Macrì Simone S Sgarra Riccardo R Ros Gloria G Maurizio Elisa E Zammitti Salvina S Milani Ornella O Onorati Marco M Vignali Robert R Manfioletti Guidalberto G
PloS one 20130725 7
High Mobility Group A proteins (HMGA1 and HMGA2) are architectural nuclear factors involved in development, cell differentiation, and cancer formation and progression. Here we report the cloning, developmental expression and functional analysis of a new multi-AT-hook factor in Xenopus laevis (XHMG-AT-hook) that exists in three different isoforms. Xhmg-at-hook1 and 3 isoforms, but not isoform 2, are expressed throughout the entire development of Xenopus, both in the maternal and zygotic phase. Lo ...[more]