Mating increases neuronal tyrosine hydroxylase expression and selectively gates transmission of male chemosensory information in female mice.

ABSTRACT: Exposure to chemosensory signals from unfamiliar males can terminate pregnancy in recently mated female mice. The number of tyrosine hydroxylase-positive neurons in the main olfactory bulb has been found to increase following mating and has been implicated in preventing male-induced pregnancy block during the post-implantation period. In contrast, pre-implantation pregnancy block is mediated by the vomeronasal system, and is thought to be prevented by selective inhibition of the mate's pregnancy blocking chemosignals, at the level of the accessory olfactory bulb. The objectives of this study were firstly to identify the level of the vomeronasal pathway at which selective inhibition of the mate's pregnancy blocking chemosignals occurs. Secondly, to determine whether a post-mating increase i

SUBMITTER: Matthews GA 

PROVIDER: S-EPMC3723660 | biostudies-literature | 2013

REPOSITORIES: biostudies-literature