Ontology highlight
ABSTRACT:
SUBMITTER: Masliah G
PROVIDER: S-EPMC3724394 | biostudies-literature | 2013 Jun
REPOSITORIES: biostudies-literature
Masliah Grégoire G Barraud Pierre P Allain Frédéric H-T FH
Cellular and molecular life sciences : CMLS 20120824 11
The double-stranded RNA binding domain (dsRBD) is a small protein domain of 65-70 amino acids adopting an αβββα fold, whose central property is to bind to double-stranded RNA (dsRNA). This domain is present in proteins implicated in many aspects of cellular life, including antiviral response, RNA editing, RNA processing, RNA transport and, last but not least, RNA silencing. Even though proteins containing dsRBDs can bind to very specific dsRNA targets in vivo, the binding of dsRBDs to dsRNA is c ...[more]