Ontology highlight
ABSTRACT:
SUBMITTER: Caner S
PROVIDER: S-EPMC3724413 | biostudies-literature | 2013 Sep
REPOSITORIES: biostudies-literature
Caner Sami S Nguyen Nham N Aguda Adeleke A Zhang Ran R Pan Yuan T YT Withers Stephen G SG Brayer Gary D GD
Glycobiology 20130604 9
Trehalose synthase (TreS) catalyzes the reversible conversion of maltose into trehalose in mycobacteria as one of three biosynthetic pathways to this nonreducing disaccharide. Given the importance of trehalose to survival of mycobacteria, there has been considerable interest in understanding the enzymes involved in its production; indeed the structures of the key enzymes in the other two pathways have already been determined. Herein, we present the first structure of TreS from Mycobacterium smeg ...[more]