Ontology highlight
ABSTRACT:
SUBMITTER: Simon MM
PROVIDER: S-EPMC3724459 | biostudies-literature | 2012 Oct
REPOSITORIES: biostudies-literature
Mammalian genome : official journal of the International Mammalian Genome Society 20120919 9-10
Phenotype-driven approaches in mice are powerful strategies for the discovery of genes and gene functions and for unravelling complex biological mechanisms. Traditional methods for mutation discovery are reliable and robust, but they can also be laborious and time consuming. Recently, high-throughput sequencing (HTS) technologies have revolutionised the process of forward genetics in mice by paving the way to rapid mutation discovery. However, successful application of HTS for mutation discovery ...[more]