Ontology highlight
ABSTRACT:
SUBMITTER: Garaj S
PROVIDER: S-EPMC3725097 | biostudies-literature | 2013 Jul
REPOSITORIES: biostudies-literature
Garaj Slaven S Liu Song S Golovchenko Jene A JA Branton Daniel D
Proceedings of the National Academy of Sciences of the United States of America 20130708 30
It has recently been recognized that solid-state nanopores in single-atomic-layer graphene membranes can be used to electronically detect and characterize single long charged polymer molecules. We have now fabricated nanopores in single-layer graphene that are closely matched to the diameter of a double-stranded DNA molecule. Ionic current signals during electrophoretically driven translocation of DNA through these nanopores were experimentally explored and theoretically modeled. Our experiments ...[more]