Ontology highlight
ABSTRACT:
SUBMITTER: Batty GN
PROVIDER: S-EPMC3726276 | biostudies-literature | 2010 Jun
REPOSITORIES: biostudies-literature
Batty G Nicolas GN Kantarjian Hagop H Issa Jean-Pierre JP Jabbour Elias E Santos Fabio P S FP McCue Deborah D Garcia-Manero Guillermo G Pierce Sherry S O'Brien Susan S Cortés Jorge E JE Ravandi Farhad F
Clinical lymphoma, myeloma & leukemia 20100601 3
<h4>Background</h4>To our knowledge, the feasibility of therapy with hypomethylating agents (HAs) in patients with renal insufficiency (RI) has not been examined.<h4>Patients and methods</h4>We reviewed 41 patients with a diagnosis of acute myeloid leukemia (n = 17), myelodysplastic syndromes (n = 15), and chronic myelomonocytic leukemia (n = 9) who had RI and were receiving therapy with azacitidine or decitabine. The median number of administered cycles was 3. Most patients (39; 95%) received a ...[more]