Ontology highlight
ABSTRACT:
SUBMITTER: Baucheron S
PROVIDER: S-EPMC3728480 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Baucheron Sylvie S Le Hello Simon S Doublet Benoît B Giraud Etienne E Weill François-Xavier FX Cloeckaert Axel A
Frontiers in microbiology 20130731
A screening for non-target mutations affecting fluoroquinolone susceptibility was conducted in epidemic multidrug-resistant Salmonella enterica serovar Kentucky ST198. Among a panel of representative isolates (n = 27), covering the epidemic, only three showed distinct mutations in ramR resulting in enhanced expression of genes encoding the AcrAB-TolC efflux system and low increase in ciprofloxacin MIC. No mutations were detected in other regulatory regions of this efflux system. Ciprofloxacin re ...[more]