Predictive value of pre-plus disease in retinopathy of prematurity.

ABSTRACT:

Objectives

To investigate prospectively whether the presence of pre-plus disease predicts progression to severe retinopathy of prematurity (ROP) requiring laser treatment.

Methods

Posterior retinal video recordings were obtained during 710 indirect ophthalmoscopy examinations of 214 premature infants over a period of 5 years. Two masked experts reviewed short video recordings and determined whether there was plus disease, pre-plus disease, or neither. The primary analysis included results of one examination of the right eye at 33 to 34 weeks' postmenstrual age. The primary outcome was a comparison of the proportion of eyes subsequently requiring laser treatment between the group graded as having pre-plus disease vs the group graded as having neither plus disease nor pre-plus

SUBMITTER: Wallace DK 

PROVIDER: S-EPMC3729934 | biostudies-literature | 2011 May

REPOSITORIES: biostudies-literature