Ontology highlight
ABSTRACT:
SUBMITTER: Gisselbrecht SS
PROVIDER: S-EPMC3733245 | biostudies-literature | 2013 Aug
REPOSITORIES: biostudies-literature
Gisselbrecht Stephen S SS Barrera Luis A LA Porsch Martin M Aboukhalil Anton A Estep Preston W PW Vedenko Anastasia A Palagi Alexandre A Kim Yongsok Y Zhu Xianmin X Busser Brian W BW Gamble Caitlin E CE Iagovitina Antonina A Singhania Aditi A Michelson Alan M AM Bulyk Martha L ML
Nature methods 20130714 8
Transcriptional enhancers are a primary mechanism by which tissue-specific gene expression is achieved. Despite the importance of these regulatory elements in development, responses to environmental stresses and disease, testing enhancer activity in animals remains tedious, with a minority of enhancers having been characterized. Here we describe 'enhancer-FACS-seq' (eFS) for highly parallel identification of active, tissue-specific enhancers in Drosophila melanogaster embryos. Analysis of enhanc ...[more]