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Changes in lipid density induce membrane curvature.


ABSTRACT: Highly curved bilayer lipid membranes make up the shell of many intra- and extracellular compartments, including organelles and vesicles. Using all-atom molecular dynamics simulations, we show that increasing the density of lipids in the bilayer membrane can induce the membrane to form a curved shape.

SUBMITTER: de Jesus AJ 

PROVIDER: S-EPMC3733273 | biostudies-literature | 2013 Sep

REPOSITORIES: biostudies-literature

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Changes in lipid density induce membrane curvature.

de Jesus Armando J AJ   Kastelowitz Noah N   Yin Hang H  

RSC advances 20130901 33


Highly curved bilayer lipid membranes make up the shell of many intra- and extracellular compartments, including organelles and vesicles. Using all-atom molecular dynamics simulations, we show that increasing the density of lipids in the bilayer membrane can induce the membrane to form a curved shape. ...[more]

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