Response to comment on "the geometric structure of the brain fiber pathways".
Ontology highlight
ABSTRACT:
SUBMITTER: Wedeen VJ
PROVIDER: S-EPMC3733383 | biostudies-literature | 2012 Sep
REPOSITORIES: biostudies-literature
Publications
Response to comment on "the geometric structure of the brain fiber pathways".
Wedeen Van J VJ Rosene Douglas L DL Wang Ruopeng R Dai Guangping G Mortazavi Farzad F Hagmann Patric P Kaas Jon H JH Tseng Wen-Yih I WY
Science (New York, N.Y.) 20120901 6102
In response to Catani et al., we show that corticospinal pathways adhere via sharp turns to two local grid orientations; that our studies have three times the diffusion resolution of those compared; and that the noted technical concerns, including crossing angles, do not challenge the evidence of mathematically specific geometric structure. Thus, the geometric thesis gives the best account of the available evidence. ...[more]
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