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Identification of tetrodotoxin-producing Shewanella spp. from feces of food poisoning patients and food samples.

ABSTRACT: Shewanella spp. is infrequently recovered from clinical specimens. Following two outbreaks of food poisoning, eight Shewanella spp. strains were obtained from the fecal specimens of patients, food and food processing-related materials. Tetrodotoxin (TTX) was identified in the culture supernatants of these strains, and the toxin's biological activity was detected using a mouse bioassay. This study suggested that Shewanella strains can colonize and survive in human intestines. The study also raises the issues of the accumulation of TTX produced by Shewanella in food and the possible role of TTX-producing Shewanella in food poisoning.

SUBMITTER: Wang D

PROVIDER: S-EPMC3734009 | biostudies-literature | 2013 Jun

REPOSITORIES: biostudies-literature

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Identification of tetrodotoxin-producing Shewanella spp. from feces of food poisoning patients and food samples.

Wang Duochun D Wang Yonglu Y Huang Hongnan H Lin Jie J Xiao Di D Kan Biao B

Gut pathogens 20130620 1

Shewanella spp. is infrequently recovered from clinical specimens. Following two outbreaks of food poisoning, eight Shewanella spp. strains were obtained from the fecal specimens of patients, food and food processing-related materials. Tetrodotoxin (TTX) was identified in the culture supernatants of these strains, and the toxin's biological activity was detected using a mouse bioassay. This study suggested that Shewanella strains can colonize and survive in human intestines. The study also raise ...[more]

PMID: 23782739

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