Metabolic profiling of Alzheimer's disease brains.
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ABSTRACT:
SUBMITTER: Inoue K
PROVIDER: S-EPMC3734482 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Publications
Metabolic profiling of Alzheimer's disease brains.
Inoue Koichi K Tsutsui Haruhito H Akatsu Hiroyasu H Hashizume Yoshio Y Matsukawa Noriyuki N Yamamoto Takayuki T Toyo'oka Toshimasa T
Scientific reports 20130101
Alzheimer's disease (AD) is an irreversible, progressive brain disease and can be definitively diagnosed after death through an examination of senile plaques and neurofibrillary tangles in several brain regions. It is to be expected that changes in the concentration and/or localization of low-molecular-weight molecules are linked to the pathological changes that occur in AD, and determining their identity would provide valuable information regarding AD processes. Here, we propose definitive brai ...[more]
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