Ontology highlight
ABSTRACT:
SUBMITTER: Vanhoutteghem A
PROVIDER: S-EPMC373485 | biostudies-literature | 2004 Mar
REPOSITORIES: biostudies-literature
Vanhoutteghem Amandine A Djian Philippe P
Proceedings of the National Academy of Sciences of the United States of America 20040226 10
Basonuclin is a zinc finger protein specific to basal keratinocytes and germ cells. In keratinocytes, basonuclin behaves as a stem cell marker and is thought to be a transcription factor that maintains proliferative capacity and prevents terminal differentiation. The human gene is located on chromosome 15. We have discovered in the chicken the existence of basonuclin 2, a basonuclin homolog. We also report the entire sequence of mouse and human basonuclin 2; the corresponding genes are located o ...[more]