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A penalized likelihood approach to estimate within-household contact networks from egocentric data.

ABSTRACT: Acute infectious diseases are transmitted over networks of social contacts. Epidemic models are used to predict the spread of emergent pathogens and compare intervention strategies. Many of these models assume equal probability of contact within mixing groups (homes, schools, etc.), but little work has inferred the actual contact network, which may influence epidemic estimates. We develop a penalized likelihood method to infer contact networks within households, a key area for disease transmission. Using egocentric surveys of contact behavior in Belgium, we estimate within-household contact networks for six different age compositions. Our estimates show dependency in contact behavior and vary substantively by age composition, with fewer contacts occurring in older households. Our results are relevant for epidemic models used to make policy recommendations.

SUBMITTER: Potter GE

PROVIDER: S-EPMC3736605 | biostudies-literature | 2013 Aug

REPOSITORIES: biostudies-literature

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A penalized likelihood approach to estimate within-household contact networks from egocentric data.

Potter Gail E GE Hens Niel N

Journal of the Royal Statistical Society. Series C, Applied statistics 20130801 4

Acute infectious diseases are transmitted over networks of social contacts. Epidemic models are used to predict the spread of emergent pathogens and compare intervention strategies. Many of these models assume equal probability of contact within mixing groups (homes, schools, etc.), but little work has inferred the actual contact network, which may influence epidemic estimates. We develop a penalized likelihood method to infer contact networks within households, a key area for disease transmissi ...[more]

PMID: 23935218

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